However, in the present study, only the effect of overexpressed galectin-3 on the behavior of human esophageal cancer Eca-109 cells was observed; the effect of a galectin-3-silencing gene on apoptosis in Eca-109 cancer cells has not yet been observed, although this may be analyzed in the future. The gene discussed is LGALS3; the disease is esophageal cancer.