Notably, the analysis of TRAIL levels between patients with CD with and without other concomitant autoimmune disorders (T1D, Hashimoto’s thyroiditis, Addison’s disease, vitiligo, autoimmune atrophic gastritis and psoriasis) revealed significantly lower levels in patients with other autoimmune disorders (P=0.047). Here, TNFSF10 is linked to type 1 diabetes mellitus.