SP1 and hydrops fetalis: The results showed that the expression of Sp3 mRNA, the ratio of Sp3/Sp1 in subcutaneous fat and the expression of Sp3 and Sp1 mRNA in visceral fat in RSG-treated mice had significantly increased compared with the mice in the HF group, while no statistical difference was observed in the expression of Sp1 mRNA in the subcutaneous fat in the HF and RSG groups.