To evaluate the functional role of NUF2 in pancreatic cancer, the expression levels of NUF2 were examined in 15 cases of pancreatic cancer tissues and four human pancreatic cancer cell lines, including Sw1990, PANC-1, BXPC-3, and MLA-PACA-2, as well as the HEK-293 cells. This evidence concerns the gene NUF2 and familial pancreatic carcinoma.