For the post-treatment patients with a VGPR or CR (n = 33), a smaller MALAT1 change (difference in ∆CT ≤1.5) remained the single factor predictive of early progression of multiple myeloma (OR 4.38, 95% CI 1.48-12.99; p = 0.008) (Table 3). The gene discussed is MALAT1; the disease is plasma cell myeloma.