PSEN2 and infection: Interestingly, when combining data from both treatment groups regardless of infection status, vaccine recipients had an average 0.23 loge (95% CI: [0.12, 0.35], p<0.001) lower mock responses than placebo recipients, circumcised men had an average 0.14 loge (95% CI: [0.20, 0.25], p = 0.02) higher mock responses than uncircumcised men, and Ad5 seropositive men had an average 0.23 loge (95% CI: [0.11, 0.35], p<0.001) higher mock responses than Ad5 seronegative men (Table 3).