RAB5C and cancer: Using these criteria to assess the 14 ‘cancer versus normal’ datasets and focusing solely on leukemia in Oncomine, RAB5C was overexpressed in the dataset of B-ALL patient samples harboring the t(12;21) chromosomal translocation (producing the TEL/AML-1 fusion protein oncogene) as compared to normal B-lymphoid precursors (pro/pre–B cells and immature B cells) from healthy donors [70].