To determine whether a particular component of the predicted 25(OH)D score accounted for the heterogeneity, we tested effect modification of ovarian cancer associations with rs731236, rs7975232, and VDR 3′ end haplotypes by BMI (<25 vs. 25+ kg/m2), total vitamin D intake (below vs. above median), total leisure-time physical activity (below vs. above median), menopausal status and HT use (premenopausal, postmenopausal/never HT use, postmenopausal/past HT use, and postmenopausal/current HT use), and alcohol intake (below vs. above median). This evidence concerns the gene VDR and ovarian cancer.