Moreover, significant correlations were found between FLS PGC-1β expression and CRP, ESR or DAS28 from eight RA patients (CRP: r = 0.738, P = 0.037; ESR: r = 0.762, P = 0.028; DAS28: r = 0.786, P = 0.021). This evidence concerns the gene PPARGC1B and rheumatoid arthritis.