Using quantitative reverse transcription polymerase chain reaction (RT-PCR) and IHC, Jung et al. observed elevated mRNA levels of Notch3, Jag1 and Jag2 as well as higher Notch3 and Jag2 protein expression in serous ovarian cancer samples as compared to benign controls. This evidence concerns the gene NOTCH3 and ovarian serous adenocarcinoma.