We also compared our list of SOX4 regulated genes in GBM cells to a previously published list of SOX4 regulated genes in prostate cancer cells [23], and we found that 54 genes are commonly changed in both glioma and prostate cancer in response to SOX4, with 33 genes up-regulated and 14 genes down-regulated genes (Additional file 5: Table S3). The gene discussed is SOX4; the disease is central nervous system cancer.