A case report on the transplantation of allogeneic amniotic stem cells (high percentage of CD34+ cells) in a young T1DM patient, suggests that hyperglycemia had been improved without insulin therapy during 36-month follow up, indicating that amniotic membrane stem cell transplantation can improve islet cell function in vivo (Liu et al., 2013). This evidence concerns the gene INS and Hyperglycemia.