However, OLFM4 gene sequences from 28 colon cancer samples did not show any sequence variants in a 1 kb promoter region or any of the five exons of the OLFM4 gene, although regulatory polymorphisms in intronic regions or epigenetic regulation cannot be excluded (Besson et al., 2011). The gene discussed is OLFM4; the disease is malignant colon neoplasm.