Further subgroup analysis was conducted based on cancer type, however, no association between the FOXP3 gene polymorphisms and the risk of breast cancer was revealed (for rs3761549: TT vs. CT+CC OR, 0.98, 95% CI, 0.60–1.60; TT+CT vs. CC OR, 1.01, 95% CI, 0.84–1.22; TT vs. CC OR, 0.98, 95% CI, 0.60–1.61; TC vs. CC OR, 1.02, 95% CI, 0.84–1.23; T vs. C OR, 1.01, 95% CI, 0.87–1.16. The gene discussed is FOXP3; the disease is breast cancer.