In the current study, a number of cases were reanalyzed for EGFR mutations, including minor mutations, such as exon 20 insertions and G719X in exon 18; however, no EGFR mutations were identified in the reanalyzed samples (results not shown), suggesting that erlotinib may be effective in certain patients with EGFR mutation-negative NSCLC. Here, EGFR is linked to non-small cell lung carcinoma.