Significantly high levels of HURP mRNA expression were also detected in three, MDA-MB-231, MDA-MB-435S and ZR-75-30, of the four, MDA-MB-231, MDA-MD-435S, ZR-75-30 and MCF-7, human breast cancer cell lines examined (Fig. 1C). This evidence concerns the gene DLGAP5 and breast carcinoma.