While EBNA-1 and the EBERs (latency I) have been generally thought to be the only EBV genes expressed in endemic Burkitt’s lymphoma, with a specific role in prevention of apoptosis and survival of neoplastic cells, other recent studies have found that a minor proportion of these tumours has a novel form of latency with a different and broader gene expression profile than previously thought in which the EBNA-3A, 3B, 3C and LP latent genes are expressed in the absence of EBNA-2 and LMP-1 or 2 [17]. The gene discussed is PDLIM7; the disease is Burkitt lymphoma.