Features that favour Burkitt’s lymphoma include morphology, an immunophenotype that is CD20+, CD10+, Bcl-6+, Bcl-2−, TdT−, and monotypic sIg+, with virtually all cells Ki67+ (proliferation), and a translocation involving c-Myc and IgH or IgL, without rearrangements involving the bcl-2 or bcl-6 genes [49]. The gene discussed is BCL2; the disease is Burkitt lymphoma.