Burkitt’s lymphoma, regardless of subtype typically expresses monotypic surface IgM with light chain restriction, pan-B-cell antigens, including the CD19, CD20, CD22 and CD79a and co-expresses CD10, CD38, CD43, CD77, Bcl6, and p53, but not CD5, CD23, Bcl2 (or only weakly positive in almost 20% of cases, generally adult patients), CD138 or TdT, thus suggesting follicle centre origin. This evidence concerns the gene CD5 and Burkitt lymphoma.