To test if these predicted Msi1-binding sites of p21, p27, and p53 could be occupied and their translation could been inhibited by Msi1 in cervical cancer cells, the wild-type 3′UTRs of p21, p27 and p53 as well as their mutants were inserted downstream of Luciferase vectors separately (Fig. 6B). Here, MSI1 is linked to cervical cancer.