MSI1 and malignant colon neoplasm: In recent years, the overexpression of Msi1 has been observed in many malignant tumors that appeared to be associated with a poor prognosis, such as medulloblastoma[18, 19], colon cancer[20–22], gastric cancer[23, 24], lung cancer[25], breast cancer[26] and endometrial cancer[27–29].