To further confirm that Msi1 could regulate p21, p27 and p53 by binding to the mRNA of these genes in cervical cancer cells, pMIR-REPORT luciferase vectors containing the 3′UTRs of the p21, p27 and p53 proteins were transfected to Msi1 overexpressing cells. Here, MSI1 is linked to cervical carcinoma.