LAMP3 and neoplasm: In multivariate analysis, only high LAMP3 expression remained significantly associated with poor overall survival (HR, 2.836, 95% CI, 1.762-4.567; P<0.001), so did tumor stage (HR, 1.641, 95% CI, 1.460-1.844; P<0.001), preoperative CEA (HR, 2.176, 95% CI, 1.433-3.304; P<0.001) and CA19-9 levels (HR, 1.852, 95% CI, 1.170-2.931; P=0.009) (Table 4).