LAMP3 and neoplasm: In multivariate analysis, high LAMP3 expression remained significantly associated with poor overall survival (HR, 2.519, 95% CI, 1.062-5.980; P=0.036), as did tumor differentiation (HR, 4.741, 95% CI, 2.252-9.982; P<0.001) and tumor stage (HR, 1.988, 95% CI, 1.260-3.137; P=0.003) (Table 5).