Age of over 35 was also weakly associated with lipodystrophy-related regimen modification (aHR 1.35, 95% CI 0.98-1.84, p-value = 0.06) whereas there was no association between HLA-B*40:01 (Table 3) and lipodystrophy-related modification. The gene discussed is HLA-B; the disease is lipodystrophy.