IFNA1 and asthma: We then narrowed our search taking into account the expression of targets in epithelium and their relevance to asthma and found out that the network of microRNAs showed predicted targets that mediate the TGF-β and IFN-α/IFN-β signalling pathways as well as mediators of IL-6 and IL-8 expression (Figure 2 A–D, respectively).