HLA-DRB1 and myeloid sarcoma: The reasons are not clear, and are even less understood, as DQ6-associated anti-myelin autoreactivity may also play a role in the pathogenesis of MS, as suggested from studies in some unique populations (12–14) or from our study showing that DQB1*06:02, but not DRB1*15:01, determine disease susceptibility to MOBP or PLP in HLA-Tg mice (10, 11).