PPARG and colonic neoplasm: In addition, PPARγ1 is present in human urological cancer cells (i.e., renal cell, prostate, bladder and testicular cancer) (4) and colon cancer cells (5), where ligand-dependent activation by antidiabetic drugs, such as thiazolidinediones, which include pioglitazone, rosiglitazone, troglitazone and ciglitazone, leads to apoptosis (6) and an antiproliferative effect (7).