TP53 and pituitary gland adenoma: Vogelstein et al (10) found that p53 inhibits the development of a pituitary adenoma and this function may be restrained by pleomorphic adenoma gene-like 1 in combination with reprimo, TP53-dependent G2 arrest mediator candidate, p21 and phorbol-12-myristate-13-acetate-induced protein 1.