Interestingly, in a model of murine vulvovaginal candidiasis an increased expression of AhR was observed in the vagina of both naïve and infected IDO1-deficient mice, suggesting a further mechanism of mutual transcriptional regulation between IDO1, the source of l-kyn, and its sensor AhR (38). The gene discussed is AHR; the disease is vulvovaginal candidiasis.