The analysis of negative likelihood ratios showed moderate decrease in the probability that the disease is present (LR– = 0.1–0.2) in several situations: p-tau and Aβ42/T-tau ratio in MCI cases converting to AD in ≤24 months; Aβ42/p-tau ratio in the global meta-analysis as well as in all the subgroups meta-analyses (except in MCI patients younger than 70 years and studies using ELISA technology). Here, MAPT is linked to Alzheimer disease.