EPS8 and cancer: The 97-kDa isoform of Eps8 has been variously linked to proliferation, migration and oncogenic transformation (Leu et al., 2004; Liu et al., 2010; Maa et al., 2001; Maa et al., 2007), implying that the roles of Eps8 role in cancer cell phenotypes is complex and might be dependent on context.