Multiple regression analysis revealed significant association between S100A4 serum levels, pulmonary disease activity (β = 0.369; P = 0.002), LD (β = 0.345; P = 0.005) and severity of dysphagia (β = −0.250; P = 0.033) in the whole myositis patient group. Here, S100A4 is linked to myositis disease.