IGHE and chronic obstructive pulmonary disease: Elevated serum T-IgE was found in 47.3% (129/273) of the COPD patients, and the average level of T-IgE was 401(916,2 ~ 7420) kU/L (see Table 1), both of which were significantly higher when compared with those of the control population (p < 0.001, and p < 0.001, respectively).