PER2 and Angelman syndrome: Also, we excluded CSNK1D and PER2 (circadian core set), whose mutations cause familial advanced sleep phase syndrome, as well as RAI1, BHLHE41, UBE3A, and HCRT (responsible for Smith-Magenis/Potocki-Lupski syndromes, short sleep phenotype, Angelman syndrome and narcolepsy, respectively), which had already been included in the mouse strain gene set.