Because, furin has previously been shown to indirectly regulate matrix metalloproteinases-2 and -9, and to control latent transforming growth factor beta (TGF-β) activation processing (key players in AAA pathobiology)20, 21, we evaluated whether miR-24 modulation in vitro would alter furin in human aortic SMCs. The gene discussed is FURIN; the disease is triple-A syndrome.