FoxQ1 depletion in SPC-A-1-FoxQ1 and NCI-H1395-FoxQ1 cells contributed to increased apoptotic response to various levels of chemotherapeutic reagents commonly used in lung cancer, including GEM, DDP, DOX, and PEM (Figure 6, A: P=0.003 and B: P=0.007, part data not shown). This evidence concerns the gene FOXQ1 and lung cancer.