In specialized pediatric obesity centers in Germany, Austria, and Switzerland, NAFLD (defined as aspartate aminotransferase (AST) and/or alanine transaminase (ALT) > 50 UL−1) was present in 11% of the study population of 16,390 children, but predominantly in boys, in those with extreme obesity, and in those ≥12 years of age [8]. The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.