LMNA, in addition to multiple myopathic phenotypes, also causes Charcot-Marie Tooth disease or progeria [50], [51], and SYNE1 can cause one type of Emery-Dreifuss muscular dystrophy, a dilated cardiomyopathy syndrome, a form of autosomal recessive arthrogryposis, and autosomal recessive spinocerebellar ataxia [52]–[55]. Here, SYNE1 is linked to Intellectual disability-coarse face-macrocephaly-cerebellar hypotrophy syndrome.