Given the biological targeting properties of 5b, the complex also may enable PET imaging of MDR in tumors [24], [33], [45], Pgp activity at the blood brain barrier in neurodegenerative diseases, such as Alzheimer’s disease and Parkinson disease [43], [46], as well as detection of mitochondrial myopathies in vivo[47]. This evidence concerns the gene PGP and Alzheimer disease.