LRIG2 and glioblastoma: Further, we generated glioblastoma cells with stable expressions of the full-length LRIG2 and LRIG2 ectodomain and investigated the effects of full-length LRIG2 and LRIG2 ectodomain on the proliferation and apoptosis of glioblastoma in vitro and in vivo. We then explored the possible mechanisms underlying the effects.