Examples of these are rituximab in ANCA-associated vasculitis; mepolizumab in eosinophilic granulomatosis with polyangiitis; complement 5a inhibition in ANCA vasculitis; and potentially Interleukin-6 (IL-6) inhibition with tocilizumab in large vessel vasculitis. The gene discussed is IL6; the disease is eosinophilic granulomatosis with polyangiitis.