GPLD1 and infective vaginitis: Extracellular ATP or other P2X7R agonists induced a decrease in chlamydial viability in epithelial cells, which was dependent on phospholipase D activity and blocked by treatment with P2X7R antagonists and butan-1-ol (PLD inhibitor). Also, vaginal infection was more efficient in P2X7R-deficient mice, what was correlated to higher level of acute inflammation