ATP5PO and hypothyroidism: Volta et al. reported a hypothyroidism rate of 5.7% among 70 celiac patients,27 similarly to Midhagen et al., who reported a prevalence of 5.8%.28 Velluzzi et al. evaluated 47 patients with celiac disease and 91 healthy controls, and found that the prevalence of ATPO was higher in celiac patients (29.7%) than in healthy controls (9.6%) (P < 0.001) and that thyroid echography frequently displayed a hypoechogenic pattern (42.5%).