Among five of these individuals who underwent duodenal biopsy, three presented marked subtotal villous atrophy whereas the other two showed normal histology.20 Recently, Merhdad et al. showed that there was low prevalence of positive serological tests for celiac disease (AGA IgA, EMA IgA, and TTG IgA) among 454 individuals with hypothyroidism in Iran. This evidence concerns the gene TGM2 and celiac disease.