HIF1A and infection: Although an increase in glycolysis was expected following HIF-1α stabilization and from the increase in glucose transporter 1 mRNA in cells infected with WT VACV compared with vΔC16 (Mazzon et al., 2013), consistent with the results of Fontaine et al. (2014) and Greseth & Traktman (2014), our data did not show any increase in lactate production upon infection.