The average heparanase-2 expression in the plasma of the patients with gastrointestinal carcinoma was significantly greater (39.21 ± 13.09 pixels/μg of total protein) than in the control group (25.39 ± 9.95 pixels/μg of total protein), as shown in Table 1 (P < 0.001; Student’s t test). The gene discussed is HPSE2; the disease is digestive system carcinoma.