MAPRE1 and cancer: Microtubule-associated protein RP/EB family member 1 (MAPRE1), also known as end-binding protein 1, a molecule mapped to chromosome 20q11.2, is upregulated in cancer, and induces cell proliferation and represses apoptosis through the β-catenin/T-cell factor (TCF) signaling pathway, which indicates that MAPRE1 may function as an oncogene (65).