Interestingly, Nramp-Cg and Nramp-Tg mice succumbed to oral Salmonella infection more rapidly than 129×1/SvJ mice, which showed 100% survival at day 50 post infection, with median survival values of 29 and 44 days, respectively (p<0.01 for both Cg and Tg strains compared to 129×1/SvJ). This evidence concerns the gene SLC11A1 and infection.