SLC11A1 and infection: By day 5 post infection, expression of functional Nramp1G169 in Nramp-Cg and Nramp-Tg mice led to better control of bacterial replication in both the MLN (5–10 fold lower) and spleen (>50 fold lower) compared to C57BL/6 mice expressing Nramp1D169 (Figure 3), and was not significantly different from 129×1/SvJ mice.