SLC11A1 and Salmonella Infections: Increased Nramp1 copy number did reduce splenic CFU in Nramp-Tg mice compared to Nramp-Cg mice, but bacterial titers were still 66-fold greater than in 129×1/SvJ mice (Figure 5B), demonstrating an important new finding of our study that genes other than Nramp1 are required for systemic control of chronic Salmonella infection.