Minor allele carriers of the IFNA13 promoter SNP rs641734, and IFNA21 3′UTR SNP rs2939, had a decreased risk of CRC, while the minor allele carriers of the IFNA1 missense SNP rs33965070, IFNK 3′UTR SNP rs700782, IFNAR1 3′UTR SNP rs2834202, IFNAR1 SNP rs2856968, which was genotyped instead of the promoter SNPs in the same gene, and IFNGR1 5′UTR SNP rs2234711 had an increased risk of CRC (Table 3). The gene discussed is IFNK; the disease is colorectal carcinoma.