TIMP1 and Hepatic fibrosis: Other scoring systems require special laboratory analyses such as the determination of serum hyaluronic acid (HA) [10], aminoterminal peptide of pro-collagen III (PIIINP), and the tissue inhibitor of matrix metalloproteinase 1 (TIMP-1) levels required for both the OELF (Original European Liver Fibrosis) [11] and ELF (Enhanced Liver Fibrosis) panels [12].