To our knowledge, the first cytogenetic description of t(3;8)(q27;q24) was in an 11-year-old girl with Burkitt lymphoma/leukemia arising on a background of ataxia-telangiectasia [17]; in this case, the BCL6/MYC “fusion” was subsequently translocated to other chromosome arms including 1q, 6q, 12p, 18q, and Xp as the malignancy evolved. The gene discussed is MYC; the disease is Ataxia-telangiectasia.