When removing DCIS patients, significant racial survival differences were still observed of those <65 years (P < 0.001) and ≥65 years of age (P = 0.002), married (P = 0.002), with ER+/PR+ disease (P = 0.001), undergoing modified radical mastectomy (P < 0.001), undergoing lymph node dissection (P < 0.001), undergoing adjuvant RT (P = 0.003), with nodal metastases (P < 0.001), with stage II (P = 0.005) or stage III (P = 0.005) disease, and with grade 2 (P = 0.005) or grade 3 (P = 0.016) disease. This evidence concerns the gene ESR1 and ductal breast carcinoma in situ.