Since then, aberrant overexpression of Bmi1 has been detected in several human cancers including lymphoma, acute myeloid leukemia, colorectal carcinoma, liver carcinoma, non-small cell lung cancer, breast carcinoma, prostate cancer, head and neck squamous cell carcinoma, medulloblastoma, and glioblastoma [14–23]. The gene discussed is BMI1; the disease is glioblastoma.