Since then, aberrant overexpression of Bmi1 has been detected in several human cancers including lymphoma, acute myeloid leukemia, colorectal carcinoma, liver carcinoma, non-small cell lung cancer, breast carcinoma, prostate cancer, head and neck squamous cell carcinoma, medulloblastoma, and glioblastoma [14–23]. This evidence concerns the gene BMI1 and acute myeloid leukemia.