IL1B and hydrops fetalis: After 4 and 8 weeks of the interventions, no differences were observed between any of the four treatment groups (P > 0.05); however, following 12 weeks of intervention, IL‐1β gene expression was increased in all groups (P < 0.05), with the HF‐SED and HF‐Ex groups having greater gene expression of IL‐1β than LF‐fed animals (P < 0.05); there was no attenuation of IL‐1β gene expression in the HF‐Ex group.