Notably, we extended the result of previous study which reported sST2 concentrations were greater in patients with systolic HF than those with HF with preserved ejection fraction (HFpEF) [24], and found sST2 concentrations were not significant different between systolic HF and HFpEF regarding NYHA functional class., In correlation analysis, we found patients with abnormal liver function and low albumin had higher concentrations of sST2; both have been reported to be associated with adverse events of HF [25]–[27]. Here, ALB is linked to hydrops fetalis.